週次 |
日期 |
單元主題 |
第1週 |
2/25 |
課程準備 |
第2週 |
3/04 |
Doctor Day |
第3週 |
3/11 |
郭哲倫
Cell wall contributes to the stability of plasma membrane nanodomain organization of Arabidopsis thaliana FLOTILLIN2 and HYPERSENSITIVE INDUCED REACTION1 proteins. Plant J. 101:619-636 (2020)
李佳蓉
Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody. Nat. Commun. 12:944 (2021) |
第4週 |
3/18 |
游適駿
Gα and regulator of G-protein signaling (RGS) protein pairs maintain functional compatibility and conserved interaction interfaces throughout evolution despite frequent loss of RGS proteins in plants. New Phytol. 216:562-575 (2017)
吳孟庭
DREB1A/CBF3 Is Repressed by Transgene-Induced DNA Methylation in the Arabidopsis ice1-1 Mutant. Plant Cell 32:1035-1048 (2020) |
第5週 |
3/25 |
林偉康
ACADL plays a tumor-suppressor role by targeting Hippo/YAP signaling in hepatocellular carcinoma. NPJ Precis. Oncol. 4:7 (2020)
徐立陽
The RING finger E3 ligase STRF1 is involved in membrane trafficking and modulates salt-stress response in Arabidopsis thaliana. Plant J. 82:81-92 (2015)
卓思涵
Hypoxia Induces Drug Resistance in Colorectal Cancer through the HIF-1a/miR-338-5p/IL-6 Feedback Loop. Mol. Ther. 10:1810-1824 (2019) |
第6週 |
4/01 |
溫書假 |
第7週 |
4/08 |
王梓萱
A polysaccharide isolated from the fruits of Physalis alkekengi L. induces RAW264.7 macrophages activation via TLR2 and TLR4-mediated MAPK and NF-κB signaling pathways. Int. J. Biol. Macromol. 140:895-906 (2019)
郭曄
miR-301a-PTEN-AKT Signaling Induces Cardiomyocyte Proliferation and Promotes Cardiac Repair Post-MI. Mol. Ther. Nucleic Acids 22:251-262 (2020)
許敏婕
Golden bananas in the field: elevated fruit pro-vitamin A from the expression of a single banana transgene. Plant Biotechnol. J. 15:520-532 (2017) |
第8週 |
4/15 |
林雯琪
Sumoylation stabilizes RACK1B and enhance its interaction with RAP2.6 in the abscisic acid response. Sci. Rep. 7:44090 (2017)
張卉仙
Light-Dependent Activation of the GCN2 Kinase Under Cold and Salt Stress Is Mediated by the Photosynthetic Status of the Chloroplast. Front. Plant Sci. 11:431 (2020) |
第9週 |
4/22 |
期中考週 |
第10週 |
4/29 |
黃梓斌
COLD-REGULATED GENE27 Integrates Signals from Light and the Circadian Clock to Promote Hypocotyl Growth in Arabidopsis. Plant Cell. 32:3155-3169 (2020)
林緯
PHYTOCHROME-INTERACTING FACTOR-LIKE14 and SLENDER RICE1 Interaction Controls Seedling Growth under Salt Stress. Plant Physiol. 184:506-517 (2020)
陳茂嘉
AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nat. Chem. Biol. 13:425-431 (2017) |
第11週 |
5/06 |
林家伃
Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1. Mol. Cell 81:355-369 (2021)
盧韋丞
Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation induced atrophy. Nat. Commun.. 8:1104 (2017) |
第12週 |
5/13 |
莊佳寶
Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism. Proc. Natl. Acad. Sci. USA. 117:9964-9972 (2020)
許嘉珈
Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress. Redox Biol. 20:296-306 (2019)
蘇筱晴
MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells. Cell Chem. Biol. 28:1-11 (2021) |
第13週 |
5/20 |
林筱渝
Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape. Nat. Commun. 12:469 (2021)
游博皓
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis. Nature doi: 10.1038/s41586-021-03237-4. Online ahead of print (2021)
趙重旬
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses. Nat. Commun. 12:542 (2021). |
第14週 |
5/27 |
張亭渝
A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein. Nat. Commun. 12:288 (2021).
蕭嘉鈞
Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy. Cell 184:323-333 (2021)
蔡秉叡
Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization. Cell Host & Microbe 29:477-488 (2021) |
第15週 |
6/03 |
胡力瑋
Electrophysiological and transcriptomic correlates of neuropathic pain in human dorsal root ganglion neurons. Brain 142:1215-1226 (2019)
蔡叔庭
Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer’s Disease-Related Models. Cell Rep. 30:2332-2348 (2020)
陳亭安
Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior. Proc. Natl. Acad. Sci. USA. 117: 11421-11431 (2020) |
第16週 |
6/10 |
金庭宇
PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma JCI Insight 5:e133225 (2020)
蕭鈺璇
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation. Nature 585:277-282 (2020)
蘇雋堯
Complete biosynthesis of cannabinoids and their unnatural analogues in yeast. Nature 567:123-126 (2019) |